Proteasomes
are protein complexes inside all eukaryotes and archaea, and in some bacteria.
In eukaryotes, they are located in the nucleus and the cytoplasm. The main
function of the proteasome is to degrade
unneeded or damaged proteins by proteolysis, a chemical reaction
that breaks peptide bonds. Enzymes that carry out such reactions are called
proteases. Proteasomes are part of a major mechanism by which cells regulate
the concentration of particular proteins and degrade misfolded proteins.
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